Impossible to Overdose: Unlike standard sedatives, melatonin cannot stop your breathing because it doesn't target the brain's respiratory centers. It is exceptionally safe, even at high doses.

Watch the Fall Risk: For older adults, the main risk isn't toxicity; it's the potential for falls or fractures, likely due to morning drowsiness.

The "Orphan" Drug: The reason high-dose melatonin isn't a standard cancer treatment isn't a lack of science—it's a lack of profit. Because it cannot be patented, drug companies won't fund the final approval trials.

Unconsciousness isn't Sleep: Prescription pills are excellent at sedating you, but they often sacrifice the quality of your rest to do it.

Protect the Architecture: Melatonin is one of the few options that improves sleep onset without suppressing the deep, restorative cycles (REM and Slow-Wave Sleep) that your brain actually needs to recover.

Safety Over Strength: While it may not feel as potent as a Z-drug, melatonin offers a much safer profile for long-term health, avoiding the risks of dependency and respiratory depression.